Our pharmacology research ranges from NMR structural studies of single receptors, to the modulation of cardiovascular function in entire systems.
As a team, we have particular strengths in the molecular pharmacology of G-protein coupled receptors; intracellular trafficking of receptors and transporters; the kinetics of drug-receptor interactions; the pharmacology of the cardiovascular system; and the development of new molecular tools to probe receptor structure and function.
We use these insights to tackle a variety of drug discovery challenges, with particular emphasis on cancer, cardiovascular disease and respiratory medicine. Our findings are helping to advance treatment techniques, create new drugs and, ultimately, save lives.
We collaborate closely with colleagues in the University’s School of Pharmacy on drug discovery and development, and also have extensive collaborations with industrial partners including Sosei Heptares, Promega, and AstraZeneca. Funding to support our work comes from the BBSRC, Medical Research Council, the British Heart Foundation and the British Pharmacological Society.
The newly established Centre of Membrane Proteins and Receptors (COMPARE) is a joint initiative between the universities of Nottingham and Birmingham and is leading the world in techniques for visualising single membrane proteins
Professor Steve Hill and Dr Maria Arruda head up a transatlantic partnership in drug discovery between institutions in Brazil and the UK. The 10-year partnership, funded by CAPES in Brazil and the MRC and British Council Newton Fund in the UK, delivers training and fosters international research collaborations.
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School of Life SciencesUniversity of NottinghamMedical School
Queen's Medical CentreNottingham NG7 2UH
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