Sir Peter Mansfield Imaging Centre

Liver MRI and MRS

Research in liver MRI and MRS at the SPMIC is divided into the strategic research themes of MRI acquisition and analysis methods development and the application of these techniques to translational studies. These translational studies are in close collaboration with the NIHR Nottingham Biomedical Research Centre, led by Professor Guru Aithal.

As a team we aim to develop MR methods as a tool to yield complementary information on tissue structure and function, which can be used to study disease processes and therapy.

Clinical Applications

Diagnosis and disease staging

Disease progression

Serial measures of interventions

Current Translational Studies

Compensated Cirrhosis Cohort in Nottingham (3CN)

MR for the Evaluation of Portal Hypertension (MRQuee)

Optimisation of MRE for liver disease staging (ACLAIM)

Validation of the Accuracy of Magnetic Resonance Elastography

Published Translational studies

Multi-organ assessment of compensated cirrhosis patients using quantitative magnetic resonance imaging.

Short-term changes observed in multiparametric liver MRI following therapy with direct-acting antivirals in chronic hepatitis C virus patients

Non-invasive assessment of portal hypertension using quantitative magnetic resonance imaging.

SPMIC and NIHR BRC Liver Group

Professor Sue Francis

Professor Penny Gowland

Dr Eleanor Cox

Chris Bradley

Deidre McGrath

Stephen Bawden


Professor Guru Aithal

Professor Neil Guha

Dr Naaven Palaniyappan

Dr Robert Scott