Faculty of Science

Professor Stephen Coombes

Professor of Applied Maths, School of Mathematical Sciences

stephen.coombes@nottingham.ac.uk

I am an Applied Mathematician at the University of Nottingham with a background in Theoretical Physics (BSc; 1990) and Neurocomputing (PhD; 1995).  My main research interests lie in the area of mathematical biology and in particular the application of principles from nonlinear dynamics and statistical physics to the study of neural systems.

I have made substantial contributions to models of cortical and thalamic neural tissue. These models often take the form of integro-differential equations. Their non-local nature has led to the development of a set of analytical and numerical tools for the study of waves, bumps, and patterns, based around extensions of those used for local differential equation models.

I am the co-author of a recent book (Springer, 2023) which uses techniques from modern applied mathematics to provide a perspective on Neurodynamics ranging from single neuron to tissue level, and have previously edited a book on Neural Fields (Springer, 2014) for the description of coarse-grained activity of populations of interacting neurons.   

Coombes 400x400
 

N3Centre Research Interests

Understanding neural mechanisms

 

 

Current projects

Project title: MRC Epilepsy as a dynamic disease

Funding: £185k, 2021-2025, DTP Integrated Midlands Partnership for Biomedical Training: IMPACT

Key Publications

  • Forrester M, Petros S, Cattell O, Lai YM, O'Dea RD, Sotiropoulos S, Coombes S. Whole brain functional connectivity: Insights from next generation neural mass modelling incorporating electrical synapses. PLoS Comput Biol. 2024 Dec 5;20(12):e1012647. doi: 10.1371/journal.pcbi.1012647. PMID: 39637233; PMCID: PMC11651611.

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  • Şaylı, Mustafa & Coombes, Stephen. (2023). Understanding the effect of white matter delays on large scale brain synchrony. Communications in Nonlinear Science and Numerical Simulation. 131. 107803. 10.1016/j.cnsns.2023.107803. 

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Faculty of Science

The University of Nottingham
University Park
Nottingham, NG7 2RD