| Name | Research keywords | Research techniques |
|---|
| Cinzia Allegrucci |
Cancer, stem cells, epigenetics, disease modelling, genetics |
iPSC technology, 3D cell culture models, in vitro assays, epigenetic analysis |
| Kenton Arkill |
Vascular permeability, endothelial glycocalyx, electron microscopy, correlative microscopy techniques |
Functional permeability assays, 3D TEM, correlative microscopy techniques |
| Jennifer Ashworth |
Biomaterials, fibrosis, cancer research, 3D in vitro models, imaging tissue |
3D cell culture, biomaterials design and fabrication, primary cell/ organoid culture, confocal imaging, micro-CT analysis |
| Dave Bates |
Angiogenesis, vascular remodelling, cholangiocarcinoma, renal glomerular physiology, diabetes |
In vivo imaging, RNA splicing, molecular and cellular biology, drug discovery |
| Andrew Benest |
Endothelial cells, lymphatics, angiogenesis, vasculature, transcription factors |
Transcriptomic, in vivo modelling, confocal imaging |
| Daniel Booth |
Chromosomes, mitosis, advanced-imaging, cancer, cell-division |
CLEM, electron microscopy, advanced proteomics, advanced imaging, light microscopy, volume microscopy |
| Tracey D Bradshaw |
Cancer, pharmacology, drug discovery, apoferritin, molecular mechanisms |
Tissue culture, cell biology, MTT, western blot, flow cytometry |
| Yan Chen |
Artificial intelligence, quality assurance, digital screening, medical imaging |
Programming, algorithms, artificial intelligence, DICOM image processing |
| Beth Coyle |
Paediatric brain tumours, resistance, metastasis, tumour microenvironment |
3D cell culture, apoptosis, cytotoxicity, migration assays |
| Madhumita Dandapani |
Childhood cancer, brain tumours, cancer metabolism, clinical trials, global health |
Immunohistochemistry, western blotting, cell culture, multi-omics, systematic reviews |
| Lodewijk V. Dekker |
Drug discovery, cancer, thrombosis, protein kinase, protein interactions |
Biochemical assays, cellular assays, enzyme assays, assay development, high throughput screening |
| James Dixon |
Gene therapy, gene editing, vaccines, nucleic acid delivery, regenerative medicine |
Genetic engineering/ editing, nanoformulation, reporter assays, particle characterisation, biomaterials |
| Ingrid Dreveny |
Proteases in the ubiquitin system, protein structure, structure-aided drug design, enzyme specificity, proteins in biotechnology |
Macromolecular X-ray crystallography, isothermal titration calorimetry, biochemistry, protein engineering |
| Lindy Durrant |
Cancer immunotherapy, vaccines, monoclonal antibodies, T cells, post-translational modifications |
Production of antibodies, vaccine design, cancer animal models, T cell assays, ELISA |
| Isioma Egbuniwe |
Bile duct cancer, tumour microenvironment, T and B cells, lymphatics, digital pathology |
Primary cell isolation and culture, multi-parameter flow cytometry, 3D tumour-immune cell co-culture systems, histopathology, image analysis |
| Libby Ellis |
Cancer epidemiology, population health, inequalities, cancer outcomes, health policy |
Epidemiological and statistical methodology, electronic health data analysis |
| Hester Franks |
Cancer, immunotherapy, macrophages, tumour microenvironment, melanoma |
Primary immune cell isolation and culture, flow cytometry, RNAScope |
| Kevin Gaston |
Cancer, gene regulation, transcription, cell biology, protein-DNA interactions |
RNA sequencing, ChIP sequencing, cell migration assays, cell viability assays, EMSA |
| Pavel Gershkovich |
Biopharmaceutics, pharmacokinetics, drug delivery, intestinal lymphatic transport, targeted biodistribution |
Bioanalysis, HPLC, in vivo pharmacokinetics, in vivo biodistribution, pharmacokinetic modelling and simulation |
| Anna Grabowska |
Cancer models, tumour microenvironment, target validation, drug screening, drug delivery |
Cancer modelling, 3D tissue culture, quantitative PCR, immunohistochemistry |
| Andrew Green |
Breast cancer, molecular pathology, glutamine metabolism, genotype, phenotype |
Immunohistochemistry, tissue microarrays (TMAs), laser microdissection, gene expression profiling, in situ hybridisation |
| Mohammad Ilyas |
Colorectal cancer, mutation analysis, liquid biopsy, cancer biomarkers, tissue modelling |
Histopathology, PCR, co-culture models, gene cloning |
| Andrew Jackson |
Cancer, immunotherapy, dendritic Cells (DC), T-cells, signalling |
Isolation of rare primary leukocyte subsets, flow cytometry, small molecule kinase inhibitors, multi-cellular immune culture systems |
| Victoria James |
Extracellular vesicles, RNA biology, cancer metastasis, epigenetics, inter-cellular communication |
Nanoparticle biology, RNA biology, cell biology, epigenetics |
| Sheela Jayaraman |
Gene expression, chromatin, PRH/ HHEX, cell signalling, transcriptomics |
RNAseq, western blotting, subcloning, chromatin immunoprecipitation |
| Jennie Jeyapalan |
Epigenomics, prostate cancer, transcriptional regulation, splicing |
Genomics, RNA seq analysis, molecular biology, cell culture |
| Laura Kilpatrick |
Molecular pharmacology, G protein coupled receptors, receptor tyrosine kinases, signalling complexes, protein-protein interactions |
Bioluminescence resonance energy transfer (BRET), fluorescence correlation spectroscopy, fluorescence imaging, pharmacological assays |
| Anbarasu Lourdusamy |
Brain cancer, childhood cancer, systems biology, artificial intelligence, big data |
Bioinformatics, NGS (RNAseq, ChIPseq, scRNAseq and ATAC-seq) data analysis, machine learning, statistics, high-performance computing |
| Srinvasan Madhusudan |
Medical oncology, clinical trials, breast cancer, DNA repair therapeutics, drug discovery |
DNA repair assays, immunohistochemical techniques, clinical trial methodologies |
| Anna Malecka |
Cancer, immunology, macrophages, comparative oncology, immune-stromal interactions |
Flow cytometry, stroma-Immune co-culture system, cell culture |
| Stewart Martin |
Breast, brain and ovarian cancer, radiotherapy, metastasis, novel drugs, redox homeostasis, calpain proteases |
Radiation biology, immunohistochemistry, cell and molecular biology |
| Alan McIntyre |
Cancer, hypoxia (low oxygen), acidosis, transcription, epigenetics, angiogenesis |
CRISPR CAS9, RNA-SEQ, ChIP, tumour cell phenotype assays, hypoxia and acidosis investigations |
| Cathy Merry |
Matrix biology, cancer research, disease modelling, glycobiology |
Glycobiology, hydrogel development, stem cell culture and differentiation, matrix biology, in vitro disease models |
| Nigel Minton |
Exploiting autotrophy, reducing carbon emissions, industrial biotechnology, microbial pathogenesis, anaerobes |
Synthetic biology, metabolic engineering, gas fermentation, genome editing, therapeutic delivery systems |
| Shailesh N. Mistry |
Drug discovery, chemical biology, medicinal chemistry, G protein-coupled receptors (GPCRs), allosteric modulators |
Medicinal chemistry, compound purification, spectroscopic analysis, ligand/ structure-based drug discovery |
| Nigel Mongan |
Bioinformatics, precision medicine, prostate cancer, breast cancer |
Bioinformatics, epitranscriptomics |
| Abhik Mukarjee |
Digital/molecular pathology, gastrointestinal and pancreaticobiliary cancers, translational therapeutics, inflammatory bowel disease |
Histopathology and immunohistochemistry, digital pathology and image analyses, molecular pathology, functional biology |
| Paloma Ordóñez Morán |
Stem cells, inflammation, differentiation, cancer, tumour heterogeneity |
3D organoids, primary mouse and human cell culture, stem cell-based approaches, in vivo assays, gene expression |
| Poulam Patel |
Melanoma, renal cancer, cancer immunotherapy, clinical trials, translational medicine |
Clinical trials, immune assays, |
| Ruman Rahman |
Brain cancer, cancer heterogeneity, cancer metabolism, biomaterial-based drug delivery, integrated genomics |
3D primary tumour culture, qRT-PCR, gene microarrays/ knockdowns, Western blotting, |
| Emad Rakha |
Breast cancer, pathology, classification, prognosis, digital pathology, AI, predictive and prognostic markers |
Digital pathology, immunohistochemistry, image analysis |
| Judith Ramage |
Cancer, immunology, T-lymphocytes, vaccines |
Multiplex fluorescence immunohistochemistry, T-cell assays |
| Frankie Rawson |
Wireless bioelectronics, bioelectricity, electrochemistry, bionanotechnology, bioelectronic medicine |
SECM-AFM, voltammtery, amperomerty |
| Timothy Ritzmann |
Childhood brain tumours, brain tumour immunity, childhood cancer, ependymoma, cancer recurrence |
RNA-sequencing, multiplex immunofluorescence, immunohistochemistry, clinical data analysis, childhood brain tumour clinical trials |
| Karen Robinson |
Helicobacter pylori, antimicrobial resistance, infection and immunity, gastric cancer, bacterial virulence |
Flow cytometry, real-time PCR, immunohistochemistry, antimicrobial sensitivity testing, immune cell purification and culture |
| Claire Seedhouse |
Blood cancers, drug resistance, stem cells, dormancy, functional consequences of mutations |
Quantitative PCR, flow cytometry, primary suspension cultures |
| Abdol Shams-Nateri |
Adult stem cells and cancer, precision oncology/ personalized cancer treatments, intra-tumour heterogeneity, cell signalling and transcription, ubiquitin proteasome system and F-box proteins |
3D Organoids and explants models, gene targeting and transgenics, CRISPR-Cas gene editing systems, epithelial and hematopoietic stem cells assays |
| Stuart Smith |
High grade glioma, low grade glioma, childhood brain tumours, drug delivery, tumour heterogeneity |
rtPCR, RNA methylation, IHC, FACS |
| Panos Soultanas |
DNA replication, DNA repair, replication-metabolism regulation, genome stability |
Protein expression, purification, polymerase and helicase assays, analytical ultracentrifugation, SPR |
| Ian Spendlove |
Controlling iTreg, engineering T cells, cloning TCRs from cancer patients, cancer survivors, anti cancer antibodies. |
TCR cloning/ transduction, CRISPR-Cas9 of primary leukocytes, flow sorting rare T cells, differentiating iTreg, autophagosome purification. |
| Michael Stocks |
Medicinal chemistry, drug discovery, cancer, antimicrobial resistance, prodrugs |
Synthesis, drug optimisation, drug delivery, medicinal chemistry |
| Sarah Storr |
Cancer, breast cancer, DARPP-32, calpain, cell signalling |
Cell culture, bioinformatics, immunohistochemistry, molecular biology, protein purification |
| Neil Thomas |
Enzyme mechanism, enzyme inhibitors, biopharmaceutics, silk and other protein-based biomaterials, nanobiotechnology |
Bioconjugation, chemiluminescence, un-natural amino acid mutagenesis, enzyme activity assays, enzyme inhibitor design |
| Alex Thompson |
Blood cancer, stem cell technologies, pre-clinical evaluation, next-generation models, drug discovery |
In vivo modelling, iPSC maintenance and differentiation, haematopoiesis, colony-forming assays, gene expression profiling |
| Jing Yang |
Biomaterials, 3D bioprinting, tissue engineering, regenerative medicine, immunomodulatory materials |
3D printing, biomaterial preparation, chemical characterisation, mechanical testing, cell culture |