An Introduction to Structure, Periodicity and Coordination Chemistry
This module builds on your previous studies in chemistry and provides a firm foundation in topics including: atomic and molecular structure; the shapes of molecules; chemical bonding; Lewis structures; molecular shape and symmetry; intermolecular interactions and periodic trends in the properties of the elements of the s- and p-blocks; the chemistry of the transition metal elements and their coordination complexes. You’ll spend around two hours per week studying this module with weekly tutorials.
An Introduction to Spectroscopy, Energy and Bonding in Chemistry
In this module you will learn about the development of quantum theory and the spectroscopy of the hydrogen atom. You will examine the theories used to describe the bonding in molecules and will develop an understanding of microwave and infra-red spectroscopies. The module also introduces you to some of the key concepts in thermodynamics including enthalpy, entropy and free energy and their application in describing equilibria and electrochemical processes. You will develop an understanding of the key concepts in reaction kinetics. You’ll spend two hours per week studying this module.
An Introduction to Organic Molecules and their Reactivity
You’ll examine the fundamental principles of organic chemistry. This will include nomenclature, bonding concepts, orbitals and the shape, stereochemistry and acid-base properties of organic molecules. Later in the module will focus on reactivity and important reactions and transformations in organic chemistry. You’ll spend two hours per week studying this module.
Foundation Laboratory Work
This module introduces you to the essential laboratory skills that are required in inorganic, organic and physical chemistry. You’ll spend around eight hours per week in laboratory practicals performing experiments, and collecting and analysing data. You’ll present written reports of your experimental work that will form part of the assessment for this module.
Chemistry Study Skills
You’ll follow this introductory module right at the start of your course. It is designed to develop your study skills so that you can work effectively at University. The module will also introduce you to first year undergraduate laboratory chemistry. You’ll spend around four hours in your first week in practical sessions studying this module.
You’ll be introduced to the physiology of the central nervous, cardiovascular, respiratory and urinary systems in man, including aspects of drug action. Activities will consist of lectures and associated background reading.
Chemical Calculations 1
You’ll gain a firm understanding of the use of mathematical equations in a chemical context through the study of topics including: scientific notation and significant figures; common chemical units and conversions between them; rearrangement of chemical expressions and their graphical representation. You’ll spend three hours per week in lectures and workshops for this module. Please note, if you do not possess a grade A-C in A level mathematics (or equivalent) then this module is compulsory.
Chemical Calculations 2
This module extends the material covered in Chemical Calculations 1. You’ll study topics including trigonometry, differentiation and integration, and differential equations for chemical problems. You’ll spend three hours per week in lectures and workshops studying these topics. Please note, if you do not possess a grade A-C in A level mathematics (or equivalent) then this module is compulsory.
Mathematics for Chemistry 1
You’ll be introduced to topics such as: functions of single variables; differential calculus of a single variable; integral calculus of a single variable; and basic probability and statistics. You’ll spend three hours per week in workshops and lectures for this module.
Mathematics for Chemistry 2
You’ll build upon your knowledge from Mathematics for Chemistry 1 and spend around three hours per week lectures and workshops. Topics you’ll study include: complex numbers; differential calculus; and the algebra of matrices and their applications in chemistry.
Core Laboratory Work
This module builds on the practical, analytical and communication skills developed in the first year and introduces experiments across the range of chemistry, based on your second year theory modules. You’ll spend around 10 hours per week in practicals for this module.
Equilibria, Rates and Interfaces
You’ll build upon the principles of thermodynamics and kinetics developed in your first year, applying this to gaseous and liquid bulk phases, liquid to gas and solid to gas interfaces, and electrochemical cells. You’ll spend around two hours per week in lectures and workshops studying this module.
General Inorganic Chemistry
You’ll spend two hours per week in lectures studying topics including the synthesis, bonding and reactivity of organometallic compounds, the use of symmetry and group theory to interpret infra-red spectra and NMR spectroscopy in inorganic chemistry. Further support is provided by tutorials every third week.
Quantum Chemistry and Spectroscopy
You’ll study topics including: particles and waves; vibrating molecules; orbitals; electron spin and spin-orbit coupling; Einstein coefficients; and centrifugal distortion. You’ll spend around two hours per week in lectures and one hour in workshops that run every three weeks for this module.
Medicinal Chemistry and Molecular Biology
This module introduces students to the chemistry of the fundamental building blocks of life; the structures of, and replication processes in prokaryotes; and how these can be disrupted by anti-infectives and harnessed in protein engineering. Fundamental concepts in medicinal chemistry and drug discovery are presented including the mode of action of a number of anti-cancer agents and the basic requirements for drug delivery, metabolism and targeting. You’ll spend two hours each week in lectures for this module.
Synthesis & Spectroscopy
In this module you’ll discuss the reactivity of, suggest synthetic routes for and interpret the spectroscopic characterisation of organic compounds including some natural products. Topics studied include modern spectroscopic techniques, carbon-carbon bond forming reactions, and the influence of heteroatoms on reactivity. You’ll attend two hours of lectures each week in this module and tutorials every third week.
Basic Molecular Pharmacology
You’ll study the mechanisms and gain an understanding of drug action and receptors. Areas of study will include: cell mediators; drug distribution and delivery; toxicology; and genetic factors. You’ll study this module through lectures, seminars and workshops.
Pharmacology Dissertation: Drugs and Diseases
You’ll be given the opportunity to study a disease or class of disease and rational approaches to treatments with drugs. You’ll present a 4,000 word dissertation through 50 hours of research and consideration of the relevant literature.
Advanced Laboratory Techniques
You’ll be taught advanced experimental techniques in organic, inorganic and physical chemistry, providing you with experience in experiment design and the recording, analysis and reporting of data. You’ll achieve this through a focused mini-project culminating in individual oral and written presentations and a lab report. You’ll spend around 10 hours a week in practical sessions.
Bioinorganic and Metal Coordination Chemistry
You’ll study the roles of the transition metal elements in biology including iron in haemoglobin and myoglobin, metal centres in enzymes and the use of metal complexes in medicine. You learn about the physical methods used to study the electronic structure of transition metal centres and the synthesis and the application of coordination chemistry in metal extraction, photochemistry and catalysis. You’ll spend around two hours per week in lectures, tutorials and workshops studying this module.
This module will develop your knowledge and understanding of heterogeneous and homogeneous catalysis, catalyst promotion and the concept of catalytic cycles. You’ll spend around two hours per week in lectures and seminars for this module.
Chemical Bonding and Reactivity
You’ll learn about the fundamental requirements for two molecules to react and how to assess the likelihood of reactivity based on energy level structure. You’ll learn about experiments that can probe the outcomes of reaction and experiments that can promote reaction. You’ll learn about some theoretical methods that can be used to understand reactivity. The module will progress at two lectures per week, with four workshops interspersed throughout the semester and regular problem sheets.
Organometallic and Asymmetric Synthesis
You'll learn about a range of modern reagents and synthetic methodology, and how these are applied to the synthesis of organic target molecules, such as natural products and active pharmaceuticals. You'll learn how the use of protecting groups and directing groups can be used to enable complex molecule synthesis by controlling chemoselectivity, stereoselectivity and regioselectivity, and how modern palladium-mediated cross-coupling reactions can be used to synthesise complex organic molecules.
Pericyclic Chemistry and Reactive Intermediates
In this module you will use frontier molecular orbital analysis to explain and predict stereochemical and regiochemical outcomes of pericyclic reactions. You will also learn about the generation and use of reactive intermediates in synthesis such as radicals, carbenes and nitrenes. You will spend two hours in lectures per week in this module and will attend tutorials every three weeks.
Solids, Surfaces and Interfaces
You’ll study the relationships between structure and properties of solids, and develop electronic structure theories that account for a wide range of properties of solids. You’ll learn about semi-conductors, photoconductivity, LEDs and solar cells and attend around two lectures per week in this module.
Chemical Biology and Enzymes
In this module you’ll develop an understanding of the basic principles of protein expression, mutagenesis and purification. Areas you’ll consider include: yeast two and three hybrid technology; microarrays; protein NMR; and protein X-ray crystallography. You’ll spend around two hours per week studying for this module.
Contemporary Drug Discovery
This module explores modern approaches to drug discovery and will involve discussions on how chemical structure influences the molecular properties, biological activity, and toxicity of drugs. Many examples from case histories of successful medicines will be used to illustrate the underlying chemical principles.
In this module, you’ll spend around eight hours per week on placement in a school, teaching in a classroom. You will attend training sessions and you’ll keep a journal, provide a lesson pack and give a presentation on your experiences being a classroom assistant. These will form the basis for assessment in this module.
Drug discovery: the development of new medicines
You’ll explore the vital role of chemistry in drug discovery, involving discussions of the way chemical structure influences the molecular properties, biological activity, and toxicity of drugs. Many examples from case histories of successful medicines will be used to illustrate the underlying chemical principles. This module is taught through nine interactive workshops presented by experienced medicinal chemists from GlaxoSmithKline and staff in the School of Chemistry.
This module will introduce you to molecular modelling with a focus on applications in the pharmaceutical chemistry. You will study the computer simulation of the properties of molecules and learn about molecular modelling techniques in drug discovery.
Topics in Inorganic Chemistry
You’ll study aspects of solid state materials chemistry and f-Block chemistry including their synthesis, technological uses and applications, electronic structure, spectroscopy and optical properties, magnetism and roles in catalysis.
Protein Folding and Biospectroscopy
You’ll develop an understanding of protein structure and the methods for structural analysis. A range of experimental techniques will be introduced to examine stability and to probe the nature of the active site in a range of proteins. You’ll spend around two hours per week in lectures and workshops studying this module.
The modules we offer are inspired by the research interests of our staff and as a result may change for reasons of, for example, research developments or legislation changes. The above list is a sample of typical modules we offer, not a definitive list.