Introduction to Structure, Periodicity and Coordination Chemistry
This module builds on your previous studies in chemistry and provides a firm foundation in topics including: atomic and molecular structure; the shapes of molecules; chemical bonding; Lewis structures; molecular shape and symmetry; Intermolecular interactions and periodic trends in the properties of the elements of the s- and p-blocks; the chemistry of the transition metal elements and their coordination complexes. You’ll attend two lectures per week for this module.
Introduction to Spectroscopy, Energy and Bonding in Chemistry
In this module you will learn about the development of quantum theory and the spectroscopy of the hydrogen atom. You will examine the theories used to describe the bonding in molecules and will develop an understanding of microwave and infra-red spectroscopies. The module also introduces you to some of the key concepts in thermodynamics including enthalpy, entropy and free energy and their application in describing equilibria and electrochemical processes. You will develop an understanding of the key concepts in reaction kinetics. You’ll attend two lectures per week for this module.
Introduction to Organic Molecules and their Reactivity
You’ll examine the fundamental principles of organic chemistry. This will include nomenclature, bonding concepts, orbitals and the shape, stereochemistry and acid-base properties of organic molecules. Later the module will focus on reactivity and important reactions and transformations in organic chemistry. You’ll attend two lectures per week for this module.
Foundation Laboratory Work
This module introduces you to the essential laboratory skills that are required in inorganic, organic and physical chemistry. You’ll spend around eight hours per week in laboratory practicals performing experiments, and collecting and analysing data. You’ll present written reports of your experimental work that will form part of the assessment for this module.
Chemistry Study Skills
You’ll follow this introductory module right at the start of your course. It is designed to develop your study skills so that you can work effectively at University. The module will also introduce you to first year undergraduate laboratory chemistry. You’ll spend around four hours in your first week in practical sessions studying this module.
Calculations in Chemistry
You’ll gain a firm understanding of the use of mathematical equations in a chemical context.
You’ll be introduced to the physiology of the central nervous, cardiovascular, respiratory and urinary systems in man, including aspects of drug action. Activities will consist of lectures and associated background reading.
You’ll gain a firm understanding of the use of mathematical equations in a chemical context through the study of topics including: scientific notation and significant figures; common chemical units and conversions between them; the rearrangement of chemical expressions and their graphical representation; trigonometry, differentiation and integration, and differential equations for chemical problems.
This module is compulsory for students not offering A-level mathematics (or equivalent); optional for students offering A-level mathematics or equivalent.
Core Laboratory Work
This module builds on the practical, analytical and communication skills developed in the first year and introduces experiments across the range of chemistry, based on your second year theory modules. You’ll spend around 10 hours per week in practicals for this module.
General Inorganic Chemistry
You’ll spend two hours per week in lectures studying topics including the synthesis, bonding and reactivity of organometallic compounds, the use of symmetry and group theory to interpret infra-red spectra and NMR spectroscopy in inorganic chemistry. Further support is provided by tutorials every third week.
Energy, Specrroscopy and Solid State Chemistry
In this module you'll study the physical principles underlying chemical phenomena, with emphasis on energy, quantum mechanics and spectroscopy. You'll also be introduced to solid-state chemistry, including the structure, characterisation, energetics and the band theory of solids. You’ll attend two hours of lectures each week in this module.
Synthesis and Spectroscopy
In this module you’ll discuss the reactivity of, suggest synthetic routes for and interpret the spectroscopic characterisation of organic compounds including some natural products. Topics studied include modern spectroscopic techniques, carbon-carbon bond forming reactions, and the influence of heteroatoms on reactivity. You’ll attend two lectures each week in this module and tutorials every third week.
Medicinal Chemistry and Molecular Biology
This module introduces students to the chemistry of the fundamental building blocks of life; the structures of, and replication processes in prokaryotes; and how these can be disrupted by anti-infectives and harnessed in protein engineering. Fundamental concepts in medicinal chemistry and drug discovery are presented including the mode of action of a number of anti-cancer agents and the basic requirements for drug delivery, metabolism and targeting. You’ll attend two lectures per week for this module.
Basic Molecular Pharmacology
You’ll study the mechanisms and gain an understanding of drug action and receptors. Areas of study will include: cell mediators; drug distribution and delivery; toxicology; and genetic factors. You’ll study this module through lectures, seminars and workshops.
Pharmacology Dissertation: Drugs and Diseases
You’ll be given the opportunity to study a disease or class of disease and rational approaches to treatments with drugs. You’ll present a 4,000 word dissertation through 50 hours of research and consideration of the relevant literature.
Advanced Laboratory Techniques
You’ll be taught advanced experimental techniques in organic, inorganic and physical chemistry, providing you with experience in experiment design and the recording, analysis and reporting of data. You’ll achieve this through a focused mini-project culminating in individual oral and written presentations and a lab report. You’ll spend around 10 hours a week in practical sessions.
Bioinorganic and Metal Coordination Chemistry
You’ll study the roles of the transition metal elements in biology including iron in haemoglobin and myoglobin, metal centres in enzymes and the use of metal complexes in medicine. You'll learn about the physical methods used to study the electronic structure of transition metal centres and the synthesis and the application of coordination chemistry in metal extraction, photochemistry and catalysis. You’ll attend two lectures per week in this module.
This module will develop your knowledge and understanding of heterogeneous and homogeneous catalysis, catalyst promotion and the concept of catalytic cycles. You’ll attend two lectures per week in this module.
Chemical Bonding and Reactivity
You’ll learn about the fundamental requirements for two molecules to react and how to assess the likelihood of reactivity based on energy level structure. You’ll learn about experiments that can probe the outcomes of reaction and experiments that can promote reaction. You’ll learn about some theoretical methods that can be used to understand reactivity.You'll attend two lectures per week in this module.
Organometallic and Asymmetric Synthesis
You'll learn about a range of modern reagents and synthetic methodology, and how these are applied to the synthesis of organic target molecules, such as natural products and active pharmaceuticals. You'll learn how the use of protecting groups and directing groups can be used to enable complex molecule synthesis by controlling chemoselectivity, stereoselectivity and regioselectivity, and how modern palladium-mediated cross-coupling reactions can be used to synthesise complex organic molecules.
Pericyclic Chemistry and Reactive Intermediates
In this module you will use of frontier molecular orbital analysis to explain and predict stereochemical and regiochemical outcomes of pericyclic reactions. You will also learn about the generation and use of reactive intermediates in synthesis such as radicals, carbenes and nitrenes. You'll attend two lectures per week in this module and attend a tutorial every three weeks.
Solids, Interfaces and Surfaces
You’ll study the relationships between structure and properties of solids, and develop electronic structure theories that account for a wide range of properties of solids. You’ll learn about semi-conductors, photoconductivity, LEDs and solar cells and attend around two lectures per week in this module.
Contemporary Drug Discovery
This module explores modern approaches to drug discovery and will involve discussions on how chemical structure influences the molecular properties, biological activity, and toxicity of drugs. Many examples from case histories of successful medicines will be used to illustrate the underlying chemical principles.
In this module, you’ll spend around eight hours per week on placement in a school, teaching in a classroom. You will attend training sessions and you’ll keep a journal, provide a lesson pack and give a presentation on your experiences being a classroom assistant. These will form the basis for assessment in this module.
Chemical Biology and Enzymes
In this module you’ll develop an understanding of the basic principles of protein expression, mutagenesis and purification. Areas you’ll consider include: yeast two and three hybrid technology; microarrays; protein NMR; and protein X-ray crystallography. You’ll attend two lectures per week for this module.
Topics in Inorganic Chemistry
You’ll study aspects of solid state materials chemistry and f-Block chemistry including their synthesis, technological uses and applications, electronic structure, spectroscopy and optical properties, magnetism and roles in catalysis.
Lasers in Chemistry
You'll explore the applciations of lasers in chemistry including their use in atmospheric measurements; combustion; photochemistry and synthesis; chemical kinetics; studies of small metal clusters and nanoparticles and time-resolved studies.
Drug discovery: the development of new medicines
You’ll explore the vital role of chemistry in drug discovery, involving discussions of the way chemical structure influences the molecular properties, biological activity, and toxicity of drugs. Many examples from case histories of successful medicines will be used to illustrate the underlying chemical principles. This module is taught through nine interactive workshops presented by experienced medicinal chemists from GlaxoSmithKline and staff in the School of Chemistry.
Protein Folding and Biospectroscopy
You’ll develop an understanding of protein structure and the methods for structural analysis. A range of experimental techniques will be introduced to examine stability and to probe the nature of the active site in a range of proteins. You’ll attend two lectures per week for this module.
Molecular Microbiology and Infections
In this module you’ll study the molecular biology of information processing in bacteria including protein-protein and protein-nucleic acid interactions in DNA repair, recombination, replication, transcription and translation and the use of these organisms in biotechnology. You'll also study the biology and biological chemistry of emerging or recently emerged viral and bacterial diseases that are important for public health for example HIV, avian influenza, and antibiotic resistant 'superbugs'.
Chemistry Research Project
You will be welcomed into one of the research groups within the School of Chemistry to undertake an in-depth research project. All projects will involve a review of relevant published work and the planning and execution of a research topic under the guidance of two supervisors.
Advanced Physical Chemistry
Building on your knowledge from the previous years' modules in inorganic chemistry, you’ll study topics including: electron transfer pathways; inorganic chemistry in biological systems; the principles of molecular and supramolecular photochemistry; applications of inorganic photochemistry; and photocatalysis. You’ll attend two lectures each week in this module.
Contemporary Physical Chemistry
You’ll learn about the properties of matter from condensed matter through to gas phase including the novel states of matter such as ultracold molecules in traps and liquid He nanodroplets, microsolvated clusters, and low dimensional carbon structures. You’ll study the dynamics of chemical processes and the capability of modern light sources allowing for the study of time-resolved measurements on timescales ranging from pico to attoseconds. You’ll study this module in two lectures per week.
Contemporary Organic Synthesis and the Construction of Bioactive Targets
You’ll focus on the synthesis of a variety of architecturally complex bioactive targets, with particular reference to the goals and achievements of targeted synthesis. There is a particular emphasis on the use of modern synthetic methodology to address problems such as chemoselectivity, regiocontrol, stereoselectivity and atom economy. You’ll study this module in two lectures per week.
Medicines from Nature and Pharmaceutical Process Chemistry
In this module you’ll will study the role that natural products from plants, micro-organisms and marine life play in providing leads for today’s drugs and medicines in the fight against cancer, blood pressure, pain, inflammation, bacterial infection, AIDS, Alzheimer’s, Parkinson’s and other diseases. You'll also study how the discovery of biological activity in a natural product can be turned into a useful medicine, and learn about the biosyntheses and total syntheses of natural products. You will attend two lectures per week for this module.
Nucleic Acids and Bio-organic Mechanism
In this module you’ll explore the structure, chemistry and molecular recognition of nucleic acids, together with the chemical reactivity of DNA towards mutagens, carcinogens and ionising radiation and anti-tumour drugs. You will also study the chemistry of the coenzymes derived from vitamins and their biological, together with their roles in nutrition. You will attend two lectrues per week in this module.
Inorganic and Materials Chemistry
In this module you will explore inorganic photochemistry, electron transport pathways, molecular and supramolecular photochemistry, and artificial photosynthesis together with the principles that underpin green chemistry. You will attend two lectures per week in this module.
Self-assembly and Bottom-up Approaches to Nanostructure Fabrication
In this module you’ll study the approaches to the fabrication of molecular assemblies on the nanoscale. You’ll gain an understanding of the nature of intermolecular forces, paying particular attention to their application to self-assembly. You’ll attend two lectures per week in this module.
Enterprise for Chemists
You’ll understand how companies within the chemical sector operate and integrate into the economy and learn about their structure and organisation and how these contribute to form a successful business.
You’ll learn about the factors that lead to successful innovation, including evaluation and management of an idea or concept in chemistry. In addition, you’ll consider the factors required to extract value from a product or concept, and the potential marketing routes available from both an academic and industrial viewpoint.
You’ll develop an understanding of intellectual property, how it is protected and used to create value in the business context. Relevant aspects of intellectual property law will be highlighted, including patents, trademarks, copyright, and trade secrets, with an examination of their relevance and everyday application within the chemistry industries.
Advanced Biocatalysis, Biosynthesis and Chemical Biology
In this module you'll explore protein synthesis, chemical genetics approaches to drug discovery and activity based profiling/ proteomics. You'll also review the application of enzymes in organic synthesis and gain a molecular view of biosynthetic pathways.
The modules we offer are inspired by the research interests of our staff and as a result may change for reasons of, for example, research developments or legislation changes. The above list is a sample of typical modules we offer, not a definitive list.