School of Life Sciences
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Advanced Microscopy Unit

The AMU is a dedicated microscopy facility based in the Medical School. It is part of the School of Life Sciences Imaging (SLIM) facility.

The AMU is equipped for microscopy and tissue preparation including: light and electron microscopy, fluorescence, confocal and time-lapse microscopy, preparation techniques for tissues, cells, materials and tissue engineered constructs and software for quantitative image reconstruction, tracking and analysis.

For further information on the range of facilities we offer, select your area of interest below:

 

 

 

 

 

 

Recent AMU Publications

 Jennifer T. Patel, Hannah R. Belsham, Alexandra J. Rathbone, Bill Wickstead, Christopher Gell, Claire T. Friel The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition Open Biol. 2016 6 160223; DOI: 10.1098/rsob.160223.

Dunajová L, Cash E, Markus R, Rochette S, Townley AR, Wheatley SP. The NH2terminus of survivin is a mitochondrial targeting sequence and C-Src regulator. JCell Sci. 2016 May 31. pii: jcs.183277. 

Xu L, Nwosu LN, Burston JJ, Millns PJ, Sagar DR, Mapp PI, Meesawatsom P, Li L,Bennett AJ, Walsh DA, Chapman V. The anti-NGF antibody muMab 911 both preventsand reverses pain behaviour and subchondral osteoclast numbers in a rat model of osteoarthritis pain. Osteoarthritis Cartilage. 2016 May 18. pii:S1063-4584(16)30101-7. doi: 10.1016/j.joca.2016.05.015

Goode A, Butler K, Long J, Cavey J, Scott D, Shaw B, Sollenberger J, Gell C, Johansen T, Oldham NJ, Searle MS, Layfield R. Defective recognition of LC3B bymutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism inALS-FTLD. Autophagy. 2016 May 9:1-11.

Loreto, A, Di Stefano, M, Gering, M, and Conforti1, L. Wallerian Degeneration Is Executed by an NMN-SARM1-Dependent Late Ca2+ Influx but Only Modestly Influenced by Mitochondria. Cell Reports. 2015 http://dx.doi.org/10.1016/j.celrep.2015.11.032

Behnke JM, Stewart A, Bajer A, Grzybek M, Harris PD, Lowe A, Ribas A, Smales L, Vandegrift KJ. Bank voles (Myodes glareolus) and house mice (Mus musculusmusculus; M. m. domesticus) in Europe are each parasitized by their own distinct species of Aspiculuris (Nematoda, Oxyurida). Parasitology. 2015 142(12):1493-505. 

Aljaberi AM, Webster JR, Wheatley SP. Mitotic activity of survivin is regulated by acetylation at K129. Cell Cycle. 2015 Jun 3;14(11):1738-47.

Find more SLIM publications.

School of Life Sciences

University of Nottingham
Medical School
Queen's Medical Centre
Nottingham NG7 2UH

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